ELLAGIC ACID MIN 99%
Product No. P05050
Ellagic acid is a fused four-ring polyphenol antioxidant found in numerous fruits and vegetables, most notably red fruits and berries, including raspberries, strawberries, blackberries, cranberries, pomegranate and some nuts including pecans and walnuts. The highest levels of ellagic acid are found in raspberries. In plants ellagic acid is present in the form of ellagitannin, which is ellagic acid bound to a sugar molecule. Plants produce ellagic acid and convert it to a form of tannin known as ellagitannins. These are glucosides which are readily hydrolysed by water to regenerate ellagic acid when the plants are eaten.
Ellagic acid was discovered in 1831. It has shown antiproliferative and antioxidant properties in a number of in vitro and small-animal studies. The antiproliferative properties of ellagic acid are due to its ability to directly inhibit the DNA binding of certain carcinogens, including nitrosamines and polycyclic aromatic hydrocarbons. As with other polyphenol antioxidants, ellagic acid has a chemoprotective effect by reducing oxidative stress.
These properties have generated interest in potential human health benefits. Ellagic acid is believed to have antioxidant, anti-mutagen and anti-cancer properties. Studies have reportedly shown anti-cancer activity on cancer cells of the breast, oesophagus, skin, colon, prostate and pancreas. More specifically, ellagic acid prevents the destruction of P53 gene by cancer cells. Ellagic acid is thought to bind with cancer causing molecules, thereby making them inactive. Ellagic acid showed also a chemoprotective effect against various chemically induced cancers.
One study indicated that oral administration of ellagic acid by rats can circumvent the carbon tetrachloride toxicity and subsequent fibrosis of the liver. Ellagic acid is also believed to be antiviral and antibacterial.
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