MAGNOLIA
Product No. P13075
Also known as Magnolia officinalis, Magnolia glauca, M. virginoana, M. acuminate and M. tripetata.
Virtually all of the magnolia bark collected for the herb market comes from cultivated supplies, and the pharmacy item is obtained by stripping the bark from stems, branches, and roots. The Chinese name for the herb - houpu - refers to the thick bark that is the unadorned portion of the plant. Magnolia bark has long, fibrous strips, with a rough outer surface, which is almost granular and pitted, and a smoother inner surface. It has a pleasant fragrance due to the biphenol compounds and essential oil present in the plant.
Magnolia bark is a traditional Chinese medicine (where it is known in TCM as houpu or hou po) used since 100 A.D. for treating "stagnation of qi" (low energy) as well as a variety of syndromes, such as digestive disturbances caused by emotional distress and emotional turmoil.
Magnolia bark is used as a general anti-stress and anti-anxiety agent - so its claims typically center on general benefits in controlling stress and anxiety. Newer claims are emerging, however, to link magnolia's anti-stress benefits with control of the body's primary stress hormone, cortisol, and the myriad health benefits associated with normal cortisol levels (versus elevated cortisol, which has been associated with obesity, diabetes, osteoporosis, memory problems and suppressed immune function).
Magnolia bark is rich in two biphenol compounds, (magnolol and honokiol), which are thought to contribute to the primary anti-stress and cortisol-lowering effects of the plant. The magnolol content of magnolia bark is generally in the range of 2-10 percent, while honokiol tends to occur naturally at 1-5 percent in dried magnolia bark. Magnolia bark also contains a bit less than 1 percent of an essential oil known as eudesmol, which is classified as a triterpene compound, and may provide some additional benefits as an antioxidant.
Two of the most popular herbal medicines used in Japan, one called saiboku-to and another called hange-kobuku-to, contain magnolia bark and have been used for treating ailments from bronchial asthma to depression to anxiety. Japanese researchers have determined that the magnolol and honokiol components of Magnolia officinalis are one thousand times more potent than alpha-tocopherol (vitamin E) in their antioxidant activity, thereby offering a potential heart-health benefit. Other research groups have shown both magnolol and honokiol to possess powerful "brain-health" benefits via their actions in modulating the activity of various neurotransmitters and related enzymes in the brain (increased choline acetyltransferase activity, inhibition of acetylcholinesterase, and increased acetylcholine release). Numerous animal studies have demonstrated honokiol to act as a central-nervous-system depressant at high doses, but as a non-sedating anxiolytic (anti-anxiety and anti-stress) agent at lower doses. This means that a small dose of honokiol, or a magnolia bark extract standardized for honokiol content, can help to "de-stress" you without making you sleepy, while a larger dose might have the effect of knocking you out.
When compared to pharmaceutical agents such as Valium (diazepam), honokiol appears to be as effective in its anti-anxiety activity, yet not nearly as powerful in its sedative ability. These results have been demonstrated in at least half a dozen animal studies and suggest that magnolia-bark extracts standardized for honokiol content would be an appropriate approach for controlling the detrimental effects of everyday stressors without the tranquilizing side effects of pharmaceutical agents.
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