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Also known as Chaste Tree. Agnus castus grows in Mediterranean countries and central Asia. The dried fruit, which has a pepper-like aroma and flavour, is used in herbal medicine preparations.
Agnus castus contains several different constituents, including flavonoids, iridoid glycosides, and terpenoids. The whole fruit extract, rather than one of its individual constituents, appears to be necessary for medicinal activity.
The basic mechanism of action underlying agnus castus is its effect on enhancing corpus luteal development (thereby correcting a relative progesterone deficiency) via effects through the pituitary gland. Agnus castus has a profound effect on the hypothalamus and on pituitary function, helping normalise other hormones and reducing both prolactin and the estrogen/progesterone ratio.
Agnus Castus is helpful in treating;
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